Skyway Animal Hospital
Where Every Pet is Family

Your Pet's
Health Journey
Starts Here

Building lifelong relationships with St. Petersburg families and their beloved pets. Meet our caring team who treats your pets like family.

Same-day appointments available · Limited slots today
CompassionateCare
0+Years Trusted
0.0★Star Rating
LocallyOwned & Operated
Call (727) 220-2330
3258 5th Ave S, St. Petersburg, FL 33712(727) 220-2330Mon-Fri 7:30am-6pm
Adorable cat at Skyway Animal Hospital
Skyway Animal Hospital exterior - mid-century modern building
The Skyway Animal Hospital team in downtown St. Petersburg, 2026
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We've been bringing our pets to Skyway for over 25 years now. The team here treats our fur babies like their own family — because after all this time, we ARE family. There's nowhere else we'd trust with our pets.

The Martinez Family

St. Pete Natives
Skyway Animal Hospital wellness exam in progress
For Healthy Pets

Wellness Exams & Annual Checkups

The cheapest treatment is the one we catch early. An annual exam costs a fraction of the surgery, the IV fluids, and the late-night ER visit you might be paying for six months from now.

  • Nose-to-tail physical exam
  • Weight, dental, and joint check
  • Vaccine schedule review
  • Heartworm and parasite screening
  • Bloodwork for senior pets
Call (727) 220-2330
Skyway Animal Hospital staff member holding a cat in the exam room
Core & Lifestyle Protection

Vaccinations

Florida weather means year-round exposure. We tailor vaccine schedules to your pet’s actual lifestyle, not a one-size-fits-all chart.

  • Rabies (required by Florida law)
  • DHPP for dogs, FVRCP for cats
  • Bordetella for boarding and grooming
  • Lyme and leptospirosis when warranted
  • Full puppy and kitten vaccine series
Call (727) 220-2330
Pet dental cleaning at Skyway Animal Hospital
A Cleaner Mouth, A Longer Life

Dental Cleaning

80% of pets have dental disease by age 3. A clean mouth adds years to their life. It also means breath you actually want close to your face.

  • Full oral exam under anesthesia
  • Digital dental X-rays
  • Ultrasonic scaling and polishing
  • Extractions when needed
  • At-home care plan
Call (727) 220-2330
Skyway Animal Hospital surgical team performing a procedure in the in-house surgical suite
Smart Health, Smart Behavior

Spay & Neuter

Spaying and neutering protects against cancers, infections, and accidental litters. Every patient gets pre-surgical bloodwork, individualized anesthesia, and pain management. No assembly line.

  • Pre-surgical bloodwork
  • Multimodal pain management
  • Continuous anesthesia monitoring
  • Most pets go home the same day
  • Post-op meds sent home
Call (727) 220-2330
Skyway Animal Hospital heartworm testing in the lab
Year-Round in Florida

Heartworm Prevention & Testing

Florida’s mosquito season never ends. One bite from one infected mosquito can kill an unprotected pet. Prevention runs about $100-200 a year. Treatment runs $1,000-3,000 and isn’t always survivable.

  • Annual heartworm testing (sent to our local lab)
  • Monthly preventive care options
  • Combination flea/tick/heartworm products
  • Treatment protocols if your pet tests positive
  • Reminders so you never miss a dose
Call (727) 220-2330
Senior cat at Skyway Animal Hospital
Their Golden Years, Done Right

Senior Pet Care

Pets age 5 to 7 human years for every calendar year. Bi-annual exams catch kidney disease, diabetes, arthritis, and cognitive decline before symptoms show up, when they’re still treatable.

  • Bi-annual senior wellness exams
  • Senior bloodwork (CBC, chemistry, thyroid)
  • Arthritis and pain management
  • Cognitive health monitoring
  • Quality-of-life conversations
Call (727) 220-2330
Skyway Animal Hospital team member bottle-feeding a kitten
Starting Off Right

Puppy & Kitten Care

The first year sets the foundation for a lifetime. We cover everything from first shots to spay/neuter timing to the potty-training question you didn’t think to ask.

  • Full puppy or kitten exam series
  • Vaccine schedule and core boosters
  • Deworming and parasite prevention
  • Spay/neuter timing guidance
  • Nutrition and behavior advice
Call (727) 220-2330
Skyway Animal Hospital in-house surgical suite
In-House Surgical Suite

Surgery (ACL & Soft Tissue)

ACL, TPLO, soft tissue, and routine surgery in our in-house surgical suite. Save 30 to 50 percent versus specialty hospitals. No driving to Tampa.

  • ACL and TPLO orthopedic repair
  • Mass removals and tumor resections
  • Soft tissue surgery
  • Same-clinic continuity of care
  • Pain management before, during, and after
Call (727) 220-2330
Testimonials

What Our Pet Families Say

Locally owned since 1961. Read what St. Pete pet families say.

Serving St. Petersburg families with compassionate veterinary care since 1961.

1950Established
0+Years of Trust
4Star Rating
4.8
300+ reviews

Visit Our Hospital

Conveniently located in South St. Petersburg, we're here to serve you and your pets.

Skyway Animal Hospital

3258 5th Avenue South
St. Petersburg, FL 33712

Open Now

Business Hours

Monday7:30 AM - 6:00 PM
Tuesday7:30 AM - 6:00 PM
Wednesday7:30 AM - 6:00 PM
Thursday7:30 AM - 6:00 PM
Friday7:30 AM - 6:00 PM
Saturday8:00 AM - 12:00 PM
SundayClosed

Areas We Serve

St. PetersburgSouth St. PeteGulfportPinellas ParkTreasure IslandTierra Verde
Skyway Animal Hospital exterior - a welcoming veterinary clinic in St. Petersburg

Your Neighborhood Vet Since 1961

3258 5th Avenue South, St. Petersburg

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What to Expect

  • Free parking available on-site
  • Wheelchair accessible entrance
  • Comfortable waiting area
  • Same-day appointments for sick pets

Book Your Pet's Visit

Tell us about your pet and we'll reach out to schedule your visit. Or call us directly at (727) 220-2330.

4.8 Stars on GoogleTrusted Since 1961Same-Day Appointments

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Contact Information

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(727) 220-2330
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